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In-cell cryo-electron tomography reveals differential effects of type I and type II kinase inhibitors on LRRK2 filament formation and microtubule association
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| Published in: | eLife |
|---|---|
| Format: | Online Article RSS Article |
| Published: |
2026
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| _version_ | 1871928171042963457 |
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| collection | WordPress RSS FRELIP Feed Integration |
| container_title | eLife |
| description | |
| discipline_display | Biology |
| discipline_facet | Biology |
| format | Online Article RSS Article |
| genre | Journal Article |
| id | rss_article:107300 |
| institution | FRELIP |
| journal_source_facet | eLife |
| last_indexed | 2026-07-28T03:36:58.848Z |
| publishDate | 2026 |
| publishDateSort | 2026 |
| record_format | rss_article |
| spellingShingle | In-cell cryo-electron tomography reveals differential effects of type I and type II kinase inhibitors on LRRK2 filament formation and microtubule association Biology General Biology |
| sub_discipline_display | General |
| sub_discipline_facet | General |
| subject_display | Biology General Biology |
| subject_facet | Biology General Biology |
| title | In-cell cryo-electron tomography reveals differential effects of type I and type II kinase inhibitors on LRRK2 filament formation and microtubule association |
| title_alt | Crio-tomografía electrónica en células revela efectos diferenciales de inhibidores de quinasa tipo I y tipo II en la formación de filamentos de LRRK2 y la asociación con microtúbulos Cryo-tomographie électronique in cellulo révèle les effets différentiels des inhibiteurs de kinases de type I et II sur la formation de filaments LRRK2 et l'association aux microtubules Crio-tomografia eletrônica in cellula revela efeitos diferenciais de inibidores de quinase tipo I e tipo II na formação de filamentos de LRRK2 e associação com microtúbulos |
| title_auth | In-cell cryo-electron tomography reveals differential effects of type I and type II kinase inhibitors on LRRK2 filament formation and microtubule association |
| title_es_txt | Crio-tomografía electrónica en células revela efectos diferenciales de inhibidores de quinasa tipo I y tipo II en la formación de filamentos de LRRK2 y la asociación con microtúbulos |
| title_fr_txt | Cryo-tomographie électronique in cellulo révèle les effets différentiels des inhibiteurs de kinases de type I et II sur la formation de filaments LRRK2 et l'association aux microtubules |
| title_full | In-cell cryo-electron tomography reveals differential effects of type I and type II kinase inhibitors on LRRK2 filament formation and microtubule association |
| title_fullStr | In-cell cryo-electron tomography reveals differential effects of type I and type II kinase inhibitors on LRRK2 filament formation and microtubule association |
| title_full_unstemmed | In-cell cryo-electron tomography reveals differential effects of type I and type II kinase inhibitors on LRRK2 filament formation and microtubule association |
| title_pt_txt | Crio-tomografia eletrônica in cellula revela efeitos diferenciais de inibidores de quinase tipo I e tipo II na formação de filamentos de LRRK2 e associação com microtúbulos |
| title_short | In-cell cryo-electron tomography reveals differential effects of type I and type II kinase inhibitors on LRRK2 filament formation and microtubule association |
| title_sort | in-cell cryo-electron tomography reveals differential effects of type i and type ii kinase inhibitors on lrrk2 filament formation and microtubule association |
| topic | Biology General Biology |
| url | https://elifesciences.org/articles/111075 |