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A multiscale, Bayesian inference approach to augment mechanistic models of cell signaling with machine-learning predictions of binding affinity

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Published in:PLoS Computational Biology
Format: Online Article RSS Article
Published: 2026
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container_title PLoS Computational Biology
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journal_source_facet PLoS Computational Biology
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publishDate 2026
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spellingShingle A multiscale, Bayesian inference approach to augment mechanistic models of cell signaling with machine-learning predictions of binding affinity
Computer Science
General
Computer Science
sub_discipline_display General
sub_discipline_facet General
subject_display Computer Science
General
Computer Science
subject_facet Computer Science
General
Computer Science
title A multiscale, Bayesian inference approach to augment mechanistic models of cell signaling with machine-learning predictions of binding affinity
title_alt Un enfoque de inferencia bayesiana multiescala para aumentar modelos mecanicistas de señalización celular con predicciones de aprendizaje automático de afinidad de unión
Une approche d'inférence bayésienne multi-échelle pour enrichir les modèles mécanistes de signalisation cellulaire avec des prédictions d'apprentissage automatique de l'affinité de liaison
Uma abordagem de inferência bayesiana multiescala para aumentar modelos mecanísticos de sinalização celular com previsões de aprendizado de máquina de afinidade de ligação
title_auth A multiscale, Bayesian inference approach to augment mechanistic models of cell signaling with machine-learning predictions of binding affinity
title_es_txt Un enfoque de inferencia bayesiana multiescala para aumentar modelos mecanicistas de señalización celular con predicciones de aprendizaje automático de afinidad de unión
title_fr_txt Une approche d'inférence bayésienne multi-échelle pour enrichir les modèles mécanistes de signalisation cellulaire avec des prédictions d'apprentissage automatique de l'affinité de liaison
title_full A multiscale, Bayesian inference approach to augment mechanistic models of cell signaling with machine-learning predictions of binding affinity
title_fullStr A multiscale, Bayesian inference approach to augment mechanistic models of cell signaling with machine-learning predictions of binding affinity
title_full_unstemmed A multiscale, Bayesian inference approach to augment mechanistic models of cell signaling with machine-learning predictions of binding affinity
title_pt_txt Uma abordagem de inferência bayesiana multiescala para aumentar modelos mecanísticos de sinalização celular com previsões de aprendizado de máquina de afinidade de ligação
title_short A multiscale, Bayesian inference approach to augment mechanistic models of cell signaling with machine-learning predictions of binding affinity
title_sort a multiscale, bayesian inference approach to augment mechanistic models of cell signaling with machine-learning predictions of binding affinity
topic Computer Science
General
Computer Science
url https://journals.plos.org/ploscompbiol/article?id=10.1371/journal.pcbi.1014321